1.6.2 Second stage of development: Ready-to-use CDS solutions
In the treatment of farm animals, Dr. Andreas Kalcker came up against the limits of MMS. Ruminants such as cows cannot be given classical MMS orally in large quantities due to the biochemical boundary conditions in their stomachs. The bacterial digestion could possibly come to a complete standstill and thus lead to the death of the animal. Up to now, it has not been possible to inject the classic activated MMS because of its very low pH value (2.5-3). Therefore, he prepared a pH-neutral chlorine dioxide solution (pH 5.5 – 7 at 3,000 ppm) for intramuscular administration in a distillation process. These he called CDS (Chlorine Dioxide Solution). In the distillation process, classic MMS is activated without the subsequent addition of water. The resulting gas is then introduced into a second vessel containing cold water until it turns yellow.
Warning: Laypersons should not use the manufacturer procedures for CDS given in YouTube. On the one hand, it is difficult for a layman to adjust the actual chlorine dioxide concentration. On the other hand, if the wrong material is selected or the concentration is too high, an explosive gas concentration may well occur. If you breathe in too much of the chlorine dioxide gas, you can get life-threatening cyanosis.
Conclusion: This self-production of CDS should rather be left to the technically experienced!
Ready-to-use CDS solutions are supplied in only one bottle with yellowish contents. Activation is no longer necessary here.
The recommended standard concentration for CDS is 3,000 ppm or 0.3% solution. For legal reasons of product declaration, most suppliers stay just below this (i.e. e.g. 0.29%).
Advantages of CDS:
- – pH-neutral
- – less odour
- – less taste
- – much better tolerated
- – can be dosed much higher
- – fewer side effects
On the other hand, there are also some disadvantages. Many influences such as temperature, pressure and time affect the distillation process. The chlorine dioxide concentration can only be measured with test strips by dilution and within a very narrow range. Other measurement methods require expensive laboratory equipment. This is one reason for the wide variation in chlorine dioxide concentrations (from 800 to 5,000 ppm) between suppliers and products.
In addition, the freshly filled bottle must already be stored in a cool place at the supplier’s so that the escape of the gas chlorine dioxide is at least slowed down. In theory, the cold chain must also be maintained during shipping in the summer. However, this is rarely done for practical reasons. If the user then opens the bottle immediately after receipt without having placed it in the refrigerator for at least 6 hours beforehand, a large proportion of the chlorine dioxide will escape again. Also, regardless of whether you use the bottle, the shelf life is limited to 3 to 4 months in the refrigerator and cannot be extended any other way. So it’s often worth it.
to buy several bottles of ready-to-use CDS for stock or as a crisis precaution. The concentration of the active ingredient therefore decreases steadily right after the manufacturing process, during storage, delivery and at the customer’s premises.
Conclusion: For a CDS application protocol that is always the same and repeatable worldwide, it is thus unfortunately difficult to always achieve the same dosing with the same chlorine dioxide concentration with the ready-to-use and well-tolerated CDS.
Fluctuating and decreasing concentration
Unfortunately, all this often leads to the fact that the users always work with an unknown and constantly decreasing chlorine dioxide concentration when using ready-to-use CDS, which inevitably leads to different dosages and results.
Since most ready-to-use CDS solutions are obtained from activated classical MMS by the distillation process, the same low level of free chlorine contamination exists. During distillation, not only the desired chlorine dioxide gas enters the solution, but also small quantities of pure chlorine. The same possible disadvantages for particularly sensitive people apply as with the classic MMS.
According to a study by the University of Marburg, CDS produced by distillation is not very stabilized and decomposes quite quickly (even in the refrigerator).
UPDATE: Dosage of ready-to-use CDS
Many mistakes were made in the dosage of CDS in the beginning. Dr. Andreas Kalcker knows from experiments with pig-stomachs at several universities in Spain that after ingestion of MMS by the stomach acid again up to the 7-fold quantity chlorine dioxide can be reproduced. For this reason, the first MMS to CDS conversion factors of 1:4 or 1:7 on a drop basis were far too weak. It is also not possible to give a scientifically correct conversion factor, since it is a dynamic process on which many parameters such as temperature, density, etc. have an effect.
Dr. Andreas Kalcker recommends dosing CDS only in milliliters and NOT with a drop count. A dosing pipette with ml labelling (plastic syringe without cannula) is recommended for uniform dosing worldwide.
The rough conversion factor MMS to CDS is:
For external applications:
3 activated drops of MMS correspond to approx. 1ml CDS (for CDS with approx. 0.3% chlorine dioxide solution, i.e. 3,000ppm)
For oral use (with effect of gastric acid):
1 activated drop of MMS corresponds to approx. 1ml CDS (for CDS with approx. 0.3% chlorine dioxide solution, i.e. 3,000ppm)
If one had taken so far 3 activated drops of the classical MMS orally, then this is with use of CDS now 3ml, thus the 3-fold quantity!